49ers Injury Report: McCaffrey Rest, Key Players Out vs. Browns

The 49ers are managing Christian McCaffrey's workload, providing him with additional rest ahead of their Week 13 matchup against the Browns. This decision comes after McCaffrey had 31 touches in the previous game. The absence of Bethune, Okuayinonu, and Piñeiro will impact the team's depth and special teams. Okuayinonu's high-ankle sprain is expected to keep him out for multiple weeks, while Yetur Gross-Matos is expected to be back after the bye week. The return of Robert Beal from concussion protocol provides a boost to the defense.

McCaffrey was given a rest day, listed as "non injury related."

Tatum Bethune, Sam Okuayinonu, and Eddy Piñeiro are out due to injuries.

Kyle Shanahan said Okuayinonu will be out for at least a couple of weeks due to a high-ankle sprain.

Monitor the 49ers' injury updates as gameday approaches. McCaffrey's workload management and the absence of key players will be important factors in the game against the Browns. Keep an eye on the status of other players listed on the injury report, as final decisions on gameday availability will be announced closer to kickoff.

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