Melatonin Long-Term Use Linked to Increased Heart Failure Risk
New research presented at the American Heart Association's Scientific Sessions 2025 suggests a potential link between long-term melatonin us...
A new study analyzing over 130,000 adults found that long-term melatonin use (12 months or more) was associated with a higher risk of heart failure.
Melatonin users had approximately a 90% higher chance of developing heart failure over five years compared to non-users.
The study also found that melatonin users were 3.5 times more likely to be hospitalized for heart failure.
Experts caution that over-the-counter melatonin supplements are unregulated and should not be taken chronically without medical supervision.
Why this matters: These findings challenge the widely held perception of melatonin as a harmless supplement and highlight the need for further research into its long-term effects on cardiovascular health.
A recent study presented at the American Heart Association's Scientific Sessions has raised concerns about the long-term safety of melatonin supplements. The research, which analyzed the health records of over 130,000 adults with insomnia in both the US and the UK, found a significant correlation between prolonged melatonin use and an increased risk of heart failure.
While melatonin is often considered safe for short-term use (1-2 months) to aid sleep, there is limited research on its effects beyond this period. This is particularly concerning given the increasing popularity of melatonin as a readily available, over-the-counter sleep aid.
The study revealed that individuals who took melatonin for more than a year had a nearly 90% higher risk of developing heart failure over a five-year period. Additionally, they were 3.5 times more likely to be hospitalized for heart failure and had a higher overall mortality rate.
It's important to note that the study has limitations. The researchers relied on prescription records to determine melatonin use, which may not accurately reflect actual usage, especially in countries where it is available over the counter. However, experts like Carlos Egea emphasize the need for prospective trials to clarify melatonin's safety profile.
How to Prepare:
Consult with a healthcare professional before taking melatonin, especially if you have existing heart conditions or other health concerns.
Consider alternative strategies for managing insomnia, such as improving sleep hygiene, practicing relaxation techniques, or seeking cognitive behavioral therapy.
If you are currently taking melatonin long-term, discuss the potential risks and benefits with your doctor.
Who This Affects Most:
Individuals with pre-existing heart conditions.
Those who use melatonin regularly for extended periods.
People who self-medicate with melatonin without consulting a doctor.
Q: Is melatonin safe to take?
Melatonin is generally considered safe for short-term use, but long-term effects are still being studied.
Q: What are the risks of taking melatonin long-term?
Recent studies suggest a potential link between long-term melatonin use and an increased risk of heart failure.
Q: Should I stop taking melatonin?
Consult with your doctor before making any changes to your medication or supplement routine.
Long-term melatonin use may not be as harmless as previously thought.
The study highlights the importance of further research into the long-term effects of melatonin on heart health.
It's crucial to consult with a healthcare professional before taking melatonin, especially for extended periods.
Do you think this new study will change how people use melatonin? Let us know in the comments below!
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