College Football Week 2: Top Matchups and Storylines

Michigan vs. Oklahoma:: The only ranked matchup of the week features two iconic programs looking to improve after down seasons. Keep an eye on Michigan's true freshman quarterback, Bryce Underwood, facing a tough test against Brent Venables' defense.

Illinois at Duke:: No. 11 Illinois faces a crucial road test against a Duke team aiming to establish itself in the ACC. This game will be a key indicator of Illinois' College Football Playoff potential.

Iowa at Iowa State:: The Cy-Hawk Trophy is up for grabs in this tightly contested rivalry. Expect a hard-fought, low-scoring affair as these teams renew their annual battle.

Kansas at Missouri:: The Border Showdown returns after a long hiatus, adding another layer of intensity to Week 2. This rivalry game is back for the first time since 2011.

Ohio State vs Texas:: In week 1, No. 2 Ohio State welcomes top-ranked Texas in a "Game of the Century" matchup. The matchup will pit two potential Heisman Trophy frontrunners in the Buckeyes' star receiver, Jeremiah Smith, against Texas quarterback Arch Manning.

No. 11 Illinois at Duke (Noon ET, ESPN, FuboTV?ref=yanuki.com): Illinois, with quarterback Luke Altmyer, faces a significant challenge against a Duke team led by Darian Mensah.

Iowa at No. 16 Iowa State (Noon ET, FOX, FuboTV?ref=yanuki.com): Expect a physical battle in this rivalry game where points will be at a premium.

Oklahoma State at No. 6 Oregon (3:30 p.m. ET, CBS, CBSSports.com?ref=yanuki.com, CBS Sports App, Paramount+ with Showtime): Oklahoma State, without starting quarterback Hauss Hejny, faces a tough task against a strong Oregon team.

Kansas at Missouri (3:30 p.m. ET, ESPN2, FuboTV?ref=yanuki.com): The return of the Border Showdown adds historical significance to this matchup.

No. 15 Michigan at No. 18 Oklahoma (7:30 p.m. ET, ABC, FuboTV?ref=yanuki.com): The only ranked battle in Week 2, this game features Michigan's Bryce Underwood against Oklahoma's defense.

No. 2 Ohio State vs top-ranked Texas (Noon ET, FOX, FuboTV?ref=yanuki.com): Texas quarterback Arch Manning vs OSU redshirt freshman Julian Sayin.

Virginia at NC State (Noon ET, ESPN2, FuboTV?ref=yanuki.com)

Liberty at Jacksonville State (Noon ET, CBS Sports Network, CBSSports.com?ref=yanuki.com, CBS Sports App)

Baylor at No. 17 SMU (Noon ET, The CW Network, FuboTV?ref=yanuki.com)

No. 20 Ole Miss at Kentucky (3:30 p.m. ET, ABC, FuboTV?ref=yanuki.com)

Week 2 offers several key matchups that will shape the college football landscape.

Keep an eye on freshman quarterbacks making their mark early in the season.

Rivalry games like Iowa vs. Iowa State and Kansas vs. Missouri provide added excitement and historical context.