Santos' recent form has been inconsistent, with a mix of draws and a recent defeat in the Brasileiro. The team's attacking struggles and defensive vulnerabilities point to a tight match. San Lorenzo's domestic form has also been shaky, adding another layer of uncertainty. The predicted lineup for Santos includes Brazao, Igor Vinicius, Verissimo, Frias, and Ananias, while San Lorenzo is expected to field Gill, Herrera, Romana, and Montenegro. Key absentees for Santos include Neymar and Luan Peres, while San Lorenzo will be without Luciano Vietto and Gaston Hernandez.
The match is scheduled for Thursday, May 21, 2026, at Estádio Urbano Caldeira. Santos needs to take risks, while San Lorenzo can afford to be cautious. A draw is a valuable result for the visitors, but Santos needs a win to keep their qualification hopes alive.