What is NB.1.8.1?
NB.1.8.1 is a new COVID-19 variant, a descendant of the Omicron sublineage, that is being monitored by the World Health Organization (WHO).
Health / Infectious Diseases
A new COVID-19 variant, NB.1.8.1 (also known as "Nimbus"), is gaining traction worldwide, leading to increased monitoring by health organizations. First detected in January 2025, this Omicron sublineage is now present in the US, Europe, and...
NB.1.8.1, informally known as "Nimbus," has specific mutations in its spike protein that could increase its infectiousness and allow it to evade certain antibodies. Data from GISAID shows that the first known cases were registered at the end of April 2025. The WHO's risk evaluation considers the additional public health risk posed by NB.1.8.1 as low at the global level, however it continues to monitor the situation closely.
While NB.1.8.1 appears to spread more easily than previous variants, the WHO has not observed any signs that it causes increased severity. Common symptoms align with typical Omicron subvariants and include fatigue, fever, muscle aches, and a sore throat. Current Covid jabs are expected to remain effective against this variant and protect anyone infected from severe illness.
Regional trends indicate notable increases reported in India, Hong Kong, Singapore and Thailand.
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NB.1.8.1 is a new COVID-19 variant, a descendant of the Omicron sublineage, that is being monitored by the World Health Organization (WHO).
Symptoms are similar to other Omicron subvariants, including fatigue, fever, sore throat, congestion, and muscle aches.
Yes, current COVID-19 vaccines are expected to remain effective against this variant, protecting against severe illness.
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