Who is out for the Bills against the Dolphins?
A.J. Epenesa and Shaq Thompson are out.
Sports / NFL
The Buffalo Bills face the Miami Dolphins in Week 10 with several key players dealing with injuries. This report summarizes the latest updates as of November 7, 2025.
The Buffalo Bills are facing a significant injury challenge heading into their Week 10 game against the Miami Dolphins. Edge rusher A.J. Epenesa is out with a concussion, and linebacker Shaq Thompson is sidelined with a hamstring injury. Several other players, including defensive tackle DaQuan Jones, wide receiver Joshua Palmer, and cornerbacks Taron Johnson and Christian Benford, are listed as questionable.
The injuries are impacting both the defensive and offensive sides of the ball. With Epenesa out, rookie edge rusher Landon Jackson may see increased playing time. The potential absence of multiple defensive starters puts pressure on the Bills' depth. The return of Larry Ogunjobi from suspension provides some relief.
Running back James Cook's ankle injury is also a concern for fantasy football players. If Cook is unable to play, Ray Davis is expected to take over early-down work. Fantasy managers should monitor Cook's status and consider adding Davis as a valuable handcuff.
A.J. Epenesa and Shaq Thompson are out.
DaQuan Jones, Joshua Palmer, Taron Johnson, and Christian Benford are questionable.
Monitor Cook's status and consider adding Ray Davis as a waiver wire pickup.
What impact will these injuries have on the Bills' performance against the Dolphins? Share your thoughts! Share this article with others who need to stay ahead of this trend!
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