Saint Mary's defeated No. 1 overall seed UCLA 3-2, marking the first time a top national seed has lost its opening regional game since 1999.
Jacob Johnson hit two home runs for Saint Mary's, including the go-ahead homer in the ninth inning.
Other No. 4 seeds also pulled off upsets, including Milwaukee over Auburn and Little Rock over Southern Miss.
East Carolina and Ole Miss both survived 14-inning marathon games against Tennessee and Arizona State, respectively.
Florida's Brendan Lawson hit a walk-off homer to beat Rider.
Saint Mary's victory over UCLA was the biggest shocker of the day. Jacob Johnson's two home runs propelled the Gaels to a 3-2 victory. Cam Staton closed the game, securing the historic win. UCLA, which had been the top-ranked team throughout the regular season and had 26 comeback wins, couldn't rally in the final innings.
Milwaukee vs. Auburn:: Milwaukee's offensive clinic led to a 13-8 victory over Auburn, marking their first NCAA tournament win in 27 years.
Little Rock vs. Southern Miss:: Little Rock scored four runs in the ninth inning to upset Southern Miss 7-4.
St. John’s vs. Florida State:: St. John’s rallied to defeat Florida State 6-5, scoring four runs in the final two innings.
East Carolina vs. Tennessee:: East Carolina prevailed in a 14-inning duel against Tennessee, winning 7-3. Davin Whitaker and Walker Barron hit key home runs.
Ole Miss vs. Arizona State:: Ole Miss walked off against Arizona State in 14 innings, winning 7-6. Brayden Randle's single secured the victory.
Brendan Lawson's walk-off home run in the 10th inning saved Florida from an upset against Rider, winning 7-6.
Q: Who was the winning pitcher for Saint Mary's?
Cam Staton closed out the game for Saint Mary's, securing the win.
Q: Which other No. 4 seeds won their opening games?
Milwaukee defeated Auburn, and Little Rock defeated Southern Miss.
Q: Which teams played 14-inning games?
East Carolina vs. Tennessee and Ole Miss vs. Arizona State.
Underdog teams can make a significant impact in tournament play.
Momentum shifts and late-game heroics are common in college baseball.
Upsets can change the trajectory of the entire tournament.
Saint Mary's win shows that any team can beat any other on any given day.
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