49ers vs. Saints: NFL Week 2 Predictions and Injury Report

Expert Predictions:: Most sources predict a 49ers victory. Predictions range from 49ers 25-28 to Saints 17-20.

Betting Odds:: The 49ers are favored by 3 to 6.5 points, depending on the sportsbook. The over/under is set around 40.5 to 43.5 points.

Injury Reports:: Both teams have key players on the injury list. The Saints have several players with injuries, while the 49ers also have a number of players on the injury report.

How to Watch:: The game will be broadcast on FOX. Streaming options include FuboTV and NFL Sunday Ticket from YouTube for out-of-market viewers.

Arizona Republic:: 49ers 27, Saints 20

Bookies.com:: Favors 49ers to cover the spread

Sports Betting Dime:: 49ers 25.2, Saints 20

Dimers:: 49ers 25, Saints 18

Sportsnaut:: 49ers 28, Saints 17

Julian Blackmon (S): Shoulder (DNP)

Taliese Fuaga (T): Knee (DNP)

Trevor Penning (T/G): Toe (DNP)

Chase Young (DE): Calf (DNP)

Zach Wood (LS): Elbow (LP)

Velus Jones Jr. (RB): Knee (LP)

Jordan Howden (DB): Oblique (FP)

Nick Bosa (DE): NIR - Resting Player (DNP)

Yetur Gross-Matos (DE): Knee (DNP)

Jauan Jennings (WR): Shoulder (DNP)

Christian McCaffrey (RB): Calf, NIR - Resting Player (DNP)

Brock Purdy (QB): Left Shoulder, Toe (DNP)

Trent Williams (T): Knee, NIR - Resting Player (DNP)

Ben Bartch (G): Knee, Elbow (LP)

Jordan James (RB): Finger (LP)

Jordan Watkins (WR): Ankle (LP)

Luke Gifford (LB): Knee (FP)

Mac Jones (QB): Knee (FP)

Dominick Puni (G): Knee (FP)

Spread:: San Francisco -3 (-110) vs. New Orleans +3 (-110)

Moneyline:: San Francisco -165, New Orleans +140

Total:: 40.5 (Over -110, Under -110)

The 49ers are favored to win their Week 2 matchup against the Saints.

Keep an eye on the injury reports for both teams as they could impact the game.

Streaming options are available for those unable to watch on FOX.

Consider the betting odds if you're interested in placing a wager on the game.